Autosomal dominant mutation causing the dorsal ridge predisposes for dermoid sinus in Rhodesian ridgeback dogs.

The origin of the Ridge and Associated Anomalies in Rhodesian Ridgebacks

Salmon Hilbertz, N.H.C. The origin of the ridge and associated anomalies in Rhodesian Ridgebacks. Doctor’s dissertation. ISSN: 1652-6880, ISBN: 978-91-85913-32-9 The thesis presents studies on the inheritance of the dorsal hair ridge and Dermoid Sinus (DS) in Rhodesian Ridgeback dogs. DS is classified as a neural tube defect in humans. Thus, the dog is proven to be an excellent comparative mode...

Inheritance of dermoid sinus in the Rhodesian ridgeback.

OBJECTIVES TO define the mode of inheritance of dermoid sinus. METHODS A chi-squared analysis was performed on data from 46 litters produced between 1990 and 2001. Data were corrected to avoid bias in the segregation ratio. RESULTS In data from 57 litters (n=492), 82 dermoid sinus positive offspring were observed. The frequency of affected offspring in the Swedish Rhodesian ridgeback popula...

Dermoid sinus in a Rhodesian Ridgeback.

Multiple dermoid sinuses of type Vb and IIIb on the head of a Saint Bernard dog

Dermoid sinus, a congenital malformation of neural tube development, has been reported in humans and several animal species including dogs. It is typically found in the dorsal midline and commonly occurs in the Rhodesian Ridgeback breed. A case of multiple dermoid sinuses in the fronto-occipital region is described. An 11-month-old, intact female Saint Bernard dog was presented with a 2 day his...

Absence Seizures as a Feature of Juvenile Myoclonic Epilepsy in Rhodesian Ridgeback Dogs

Myoclonic epilepsy in Rhodesian Ridgeback (RR) dogs is characterized by myoclonic seizures occurring mainly during relaxation periods, a juvenile age of onset and generalized tonic-clonic seizures in one-third of patients. An 8-month-old female intact RR was presented for myoclonic seizures and staring episodes that both started at 10 weeks of age. Testing for the DIRAS1 variant indicated a hom...